- 7th Congressional District
- Freshman Rep. Ami Bera (D) was a member of the Democratic Congressional Campaign Committee's Frontline Program. The program was designed to protect vulnerable Democratic incumbents heading into the 2014 elections.
- 10th Congressional District
- Rep. Jeff Denham (R) faced a tight re-election in California's newly re-drawn districts. Denham filed a "Statement of Intention" to run for Lieutenant Governor of California but never formally entered the June 3 primary race.
- 21st Congressional District
- Freshman Rep. David Valadao (R) won a decisive election in 2012. However, the newly drawn 21st district was not a safe Republican seat. California's 21st Congressional District was a battleground district in 2014 due to it being a Democratic leaning district held by a Republican incumbent. Incumbent Valadao (R) and Amanda Renteria (D) triumphed in the blanket primary over John Hernandez (D). Valadao successfully defended his seat, defeating Renteria in the general election on November 4, 2014.
- 36th Congressional District
- After defeating incumbent Mary Bono Mack in 2012, freshman Rep. Raul Ruiz (D) was ranked as one of the most vulnerable incumbents in 2014 by The Washington Post.