| Agreement on Detainers | Corrections | 1970 | 49 |
| Agreement on Qualifications of Educational Personnel | Education | 1968 | 37 |
| Alabama-Coosa-Tallapoosa River Basin Compact | Water apportionment | 1997 | 2 |
| Animas - La Plata Project Compact | Water apportionment | 1969 | 2 |
| Apalachicola-Chattahoochee-Flint River Basin Compact | Water apportionment | 1997 | 3 |
| Appalachian States Radioactive Waste Compact | Waste; public health | 1988 | 4 |
| Arizona-California Boundary Compact | Boundaries | 1963 | 2 |
| Arizona-Nevada Boundary Compact | Boundaries | 1960 | 2 |
| Arkansas River Basin Compact of 1970 | Water apportionment | 1970 | 2 |
| Arkansas River Compact of 1949 | Water apportionment | 1949 | 2 |
| Arkansas River Compact of 1965 | Water apportionment | 1965 | 2 |
| Arkansas-Mississippi Great River Bridge Construction Compact | Infrastructure | 1985 | 2 |
| Atlantic Interstate Low-Level Radioactive Waste Management Compact | Waste | 1986 | 3 |
| Atlantic State Marine Fisheries Compact | Fisheries; Natural resource management | 1942 | 15 |
| Bay State-Ocean State Compact | Natural resource management | 2005 | 2 |
| Bear River Compact | Water apportionment | 1958 | 3 |
| Belle Fourche River Compact | Water apportionment | 1943 | 2 |
| Bi-State Criminal Justice Center Compact | Law enforcement | 1979 | 2 |
| Bi-State Development Agency Compact | Transportation; Regional planning | 1949 | 2 |
| Big Blue River Compact | Water apportionment | 1971 | 2 |
| Big Rivers Forest Fire Management Compact | Fire protection | | 4 |
| Boating Offense Compact | Law enforcement | 1992 | 2 |
| Boundary Compact Between Michigan, Wisconsin, and Minnesota | Boundaries | 1947 | 3 |
| Breaks Interstate Park Compact | Natural resource management | 1954 | 2 |
| Buffalo and Fort Erie Bridge Compact | Infrastructure | 1994 | 2 |
| Bus Taxation Proration and Reciprocity Agreement | Taxation | 1965 | 5 |
| California-Nevada Compact | Law enforcement | 1995 | 2 |
| Canadian River Compact | Water apportionment | 1951 | 3 |
| Central Interstate Low-Level Radioactive Waste Compact | Waste; Public Health | 1982 | 4 |
| Central Midwest Low-Level Radioactive Waste Compact | Waste | 1986 | 2 |
| Chesapeake Bay Commission Agreement | Natural resource management | 1980 | 3 |
| Colorado River Compact | Water apportionment | 1922 | 7 |
| Colorado River Crime Enforcement Compact | Law enforcement | 1987 | 2 |
| Columbia River Compact | Natural resource management | 1918 | 2 |
| Columbia River Gorge Compact | Natural resource management | 1987 | 2 |
| Compact for Pension Portability for Education | Education | | 2 |
| Compact on Mental Health | Public health | 1956 | 47 |
| Connecticut River Atlantic Salmon Compact | Natural resource management | 1983 | 4 |
| Connecticut River Valley Flood Control Compact | Water resources and flood control | 1953 | 4 |
| Costilla Creek Compact | Water apportionment | 1946 | 2 |
| Cumbres and Toltec Scenic Railroad Compact | Historic preservation | 1974 | 2 |
| Delaware River and Bay Authority Compact | Transportation | 1962 | 2 |
| Delaware River Basin Compact | Natural resource management | 1961 | 4 |
| Delaware River Joint Toll Bridge Compact | Infrastructure | 1935 | 2 |
| Delaware River Port Authority Compact | Infrastructure | 1932 | 2 |
| Delaware Valley Urban Area Compact | Regional planning | 1966 | 2 |
| Desert Pacific Economic Region Compact | Economic development | 1999 | 1 |
| Driver License Compact | Licensure | 1958 | 46 |
| Emergency Management Assistance Compact | Emergency management | 1996 | 55 |
| Enhanced Nursing Licensure Compact | Licensure | 2018 | 34 |
| Furlough Compact | Corrections | | 1 |
| Great Lakes Basin Compact | Natural resource management | 1955 | 8 |
| Great Lakes Forest Fire Compact | Fire protection | | 3 |
| Great Lakes-St. Lawrence River Basin Water Resources Compact | Natural resources management | 2008 | 8 |
| Great Plains Interstate Fire Compact | Fire protection | 2006 | 7 |
| Gulf States Marine Fisheries Compact | Natural resources management | 1949 | 5 |
| Health Care Compact | Healthcare | 2011 | 9 |
| Historic Chattahoochee Compact | Historic preservation | 1978 | 2 |
| Indiana-Kentucky Boundary Compact | Boundaries | 1943 | 2 |
| Interpleader Compact | Property | 1955 | 5 |
| Interstate Civil Defense and Disaster Compact | Defense | 1951 | 23 |
| Interstate Compact Defining a Portion of the Arizona-Nevada Boundary on the Colorado River | Boundary | 1960 | 2 |
| Interstate Compact for Adult Offender Supervision | Corrections | 1998 | 53 |
| Interstate Compact for Education | Education | 1965 | 47 |
| Interstate Compact for Juveniles | Corrections | 1955 | 53 |
| Interstate Compact for Mutual Military Aid in an Emergency | Emergency management | 1953 | |
| Interstate Compact on Adoption and Medical Assistance | Children | 1986 | 50 |
| Interstate Compact on Agricultural Grain Marketing | Industry regulation | 1979 | 2 |
| Interstate Compact on Educational Opportunity for Military Children | Education | 2008 | 51 |
| Interstate Compact on Industrialized/Modular Buildings | Industry regulation | 1993 | 4 |
| Interstate Compact on Licenses of Participants in Horse Racing with Pari-Mutual Wagering | Licensure | 2000 | 15 |
| Interstate Compact on Placement of Children | Children | 1963 | 52 |
| Interstate Compact on the Mentally Disordered Offender | Corrections | 1967 | 8 |
| Interstate Compact to Build a Border Fence | Boundaries | 2011 | 1 |
| Interstate Compact to Conserve Oil and Gas | Natural resource management | 1935 | 31 |
| Interstate Corrections Compact | Corrections | 1959 | 39 |
| Interstate Earthquake Emergency Compact | Emergency management | 1989 | 4 |
| Interstate Forest Fire Suppression Compact | Fire protection | 1991 | 3 |
| Interstate High Speed Intercity Rail Passenger Network Compact | Transportation; Infrastructure | 1981 | 7 |
| Interstate Insurance Product Regulation Compact | Industry regulation | 2006 | 46 |
| Interstate Insurance Receivership Compact | Industry regulation | 1996 | 3 |
| Interstate Jobs Protection Compact | Employment | | 1 |
| Interstate Library Compact | Education | 1956 | 35 |
| Interstate Mining Compact | Natural resource management | 1970 | 24 |
| Interstate Mutual Aid Compact | Public safety | 1986 | 2 |
| Interstate Rail Passenger Network Compact | Transportation | 1980 | 7 |
| Interstate Wildlife Violator Compact | Law enforcement | 1989 | 49 |
| Iowa-Nebraska Boundary Compact | Boundaries | 1943 | 2 |
| Jennings Randolph Lake Project Compact | Natural resource management | 1996 | 2 |
| Kansas and Missouri Metropolitan Culture District Compact | Regional planning | 1996 | 2 |
| Kansas City Area Transportation Compact | Transportation | 1965 | 2 |
| Kansas-Missouri Boundary Compact | Boundaries | 1949 | 2 |
| Kansas-Missouri Flood Prevention and Control Compact | Water Resources and Flood Control | 1985 | 2 |
| Klamath River Compact | Water apportionment | 1957 | 2 |
| La Plata River Compact | Water apportionment | 1925 | 2 |
| Maine-New Hampshire School District Compact | Education | 1992 | 2 |
| Maryland and Virginia Boundary Agreement of 1785 | Boundaries | 1785 | 2 |
| Menominee River Bridge Agreement | Infrastructure | 1928 | 2 |
| Merrimack River Flood Control Compact | Water resources and flood control | 1989 | 2 |
| Mid-Atlantic Forest Fire Protection Compact | Fire protection | 1988 | 7 |
| Midwest Interstate Low-Level Radioactive Waste Compact | Waste | 1985 | 6 |
| Midwest Interstate Passenger Rail Compact | Transportation | 2000 | 8 |
| Midwestern Higher Education Compact | Education | 1991 | 12 |
| Mississippi-Alabama Railroad Authority Compact | Transportation | 1992 | 2 |
| Mississippi-Louisiana-Alabama Rapid Rail Transit Compact | Transportation | 1981 | 3 |
| Missouri-Nebraska Boundary Compact | Boundaries | 1990 | 2 |
| Multi-State Reciprocity Agreement | Licensure | 1962 | 15 |
| Multistate Highway Transportation Agreement | Transportation | 1978 | 10 |
| Multistate Lottery Agreement | Lottery | 1987 | 38 |
| Multistate Tax Compact | Taxation | 1967 | 16 |
| National Crime Prevention and Privacy Compact | Law enforcement | 1999 | 34 |
| National Guard Mutual Assistance Counter-Drug Activities Compact | Law enforcement | 1998 | 11 |
| Nebraska-South Dakota Boundary Compact | Boundaries | 1989 | 2 |
| New England Compact on Involuntary Detention for Tuberculosis Control | Health; public safety | 1997 | |
| New England Higher Education Compact | Education | 1955 | 6 |
| New England Interstate Corrections Compact | Corrections | 1960 | 7 |
| New England Interstate Water Pollution Control Compact | Water pollution control | 1947 | 7 |
| New England Radiological Health Protection Compact | Public health | 1967 | 6 |
| New England State Interstate Trucking Fee Compact | Regulation; transportation | 1982 | |
| New England State Police Compact | Law enforcement | 1969 | 6 |
| New Hampshire-Massachusetts Interstate Sewage and Waste Disposal Compact | Waste | 1981 | |
| New Hampshire-Vermont Interstate Public Water Supply Compact | Water supply | 1995 | 2 |
| New Hampshire-Vermont Interstate School Compact | Education | 1963 | 2 |
| New Hampshire-Vermont Interstate Sewage and Waste Disposal Facilities Compact | Waste | 1975 | 2 |
| New Jersey-Pennsylvania Turnpike Bridge Compact | Infrastructure | 1951 | 2 |
| New York-New Jersey Port Authority Compact of 1921 | Transportation | 1921 | 2 |
| Nonresident Violator Compact | Licensure | 1977 | 43 |
| Northeast Mississippi-Northwest Alabama Railroad Authority Compact | Transportation | 1992 | 2 |
| Northeastern Forest Fire Protection Compact | Fire protection | 1949 | 7 |
| Northwest Compact on Low-Level Radioactive Waste Management Compact | Waste | 1985 | 8 |
| Northwest Wildland Fire Protection Agreement | Fire protection | 1999 | 5 |
| Ogdensburg Bridge and Port Authority Compact | Transportation | 1952 | 1 |
| Ohio River Valley Water Sanitation Compact | Water resources | 1948 | 8 |
| Oregon-California Goose Lake Interstate Compact | Water resource management | 1963 | 2 |
| Oregon-Washington Columbia River Boundary Compact | Boundaries | 1957 | 2 |
| Pacific Marine Fisheries Compact | Fisheries | 1947 | 5 |
| Pacific Ocean Resources Compact | Natural resources management | 1991 | 5 |
| Pacific States Agreement on Radioactive Materials Transportation | Health | 1988 | 2 |
| Palisades Interstate Park Compact | Natural resources management | 1937 | 2 |
| Pecos River Compact | Water apportionment | 1948 | 2 |
| Portsmouth-Kittery Bridge Compact | Infrastructure | 1936 | 2 |
| Potomac Highlands Airport Authority Compact | Transportation | 1976 | 2 |
| Potomac River Bridges Towing Compact | Infrastructure | 1991 | 3 |
| Potomac River Compact of 1958 | Natural resource management | 1962 | 2 |
| Potomac Valley Compact | Water resource management | 1940 | 5 |
| Pymatuning Lake Compact | Water resources | 1994 | 2 |
| Quad Cities Interstate Metropolitan Authority Compact | Planning | 1990 | 2 |
| Railroad Passenger Transportation Compact | Transportation | 1969 | 2 |
| Red River Compact | Water resource management | 1978 | 4 |
| Republican River Compact | Water apportionment | 1942 | 3 |
| Rio Grande Interstate Compact | Water apportionment | 1938 | 3 |
| Rocky Mountain Low-Level Radioactive Waste Compact | Waste management | 1983 | 3 |
| Sabine River Compact | Water apportionment | 1953 | 2 |
| Snake River Compact | Water apportionment | 1949 | 2 |
| South Central Forest Fire Protection Compact | Fire protection | 1953 | 5 |
| South Platte River Compact | Water apportionment | 1923 | 2 |
| Southeast Interstate Low-Level Radioactive Waste Compact | Waste | 1982 | 6 |
| Southeastern Forest Fire Protection Compact | Forest fire protection | 1954 | 10 |
| Southern Regional Education Compact | Education | 1948 | 16 |
| Southern States Energy Compact | Natural resource management | 1962 | 18 |
| Southwestern Low-Level Radioactive Waste Disposal Compact | Waste | 1987 | 4 |
| Statewide Mutual Aid Compact | Emergency management | 2002 | 1 |
| Surplus Lines Insurance Multi-State Compliance Compact | Insurance | 2011 | 9 |
| Susquehanna River Basin Compact | Natural resource management; Flood control | 1970 | 3 |
| Tahoe Conservancy Agency Compact | Water resources | 1973 | 2 |
| Tahoe Regional Planning Compact | Natural resource management | 1969 | 2 |
| Taxation of Motor Fuels Consumed by Interstate Buses | Taxation; Transportation; Industry regulation | 1965 | 2 |
| Tennessee Interstate Furlough Compact | Corrections | | 1 |
| Tennessee River Basin Water Pollution Control Compact | Pollution control | 1958 | 3 |
| Tennessee-Tombigbee Waterway Development Compact | Economic development | 1958 | 4 |
| Texas Low-Level Radioactive Waste Disposal Compact | Waste; Public health | 1985 | 2 |
| Thames River Valley Flood Control Compact | Water resources and flood control | 1957 | 2 |
| The NASDTEC Interstate Contract | Licensure; Education | 1928 | 52 |
| Tri-State Lotto Compact | Lottery | 1985 | 3 |
| Tri-State Sanitation Compact | Waste management; Water pollution | 1935 | 3 |
| Uniform Child Custody Jurisdiction and Enforcement Act | Children | 1997 | 51 |
| Uniform Unclaimed Property Act | Property | 1995 | 16 |
| Upper Colorado River Basin Compact | Water apportionment | 1948 | 5 |
| Upper Niobrara River Compact | Water apportionment | 1962 | 2 |
| Virginia and West Virginia Boundary Agreement of 1863 | Boundaries | 1863 | 2 |
| Virginia and West Virginia Boundary Compact of 1959 | Boundary | 1959 | 2 |
| Virginia and West Virginia Boundary Compact of 1998 | Boundary | 1998 | 2 |
| Virginia-District of Columbia Boundary Line Compact of 1946 | Boundaries | 1946 | 2 |
| Virginia-Kentucky Boundary Compact | Boundaries | 1800 | 2 |
| Virginia-Maryland Boundary Agreement of 1878 | Boundaries | 1878 | 2 |
| Virginia-North Carolina Boundary Agreement of 1791 | Boundaries | 1791 | 2 |
| Virginia-North Carolina Boundary Agreement of 1970 | Boundaries | 1970 | 2 |
| Virginia-Tennessee Boundary Agreement | Boundaries | 1901 | 2 |
| Wabash Valley Compact | Natural resource management | 1959 | 2 |
| Washington Metropolitan Area Transit Authority Compact | Transportation | 1960 | 3 |
| Waterfront Commission Compact | Law enforcement | 1953 | 2 |
| Western Corrections Compact | Corrections | 1959 | 11 |
| Western Interstate Energy Compact | Energy | 1970 | 12 |
| Western Regional Higher Education Compact | Education | 1951 | 15 |
| Wheeling Creek Watershed Protection and Flood Prevention Compact | Flood prevention | 1967 | 2 |
| Woodrow Wilson Bridge and Tunnel Compact | Infrastructure | 1995 | 3 |
| Yellowstone River Compact | Interstate water apportionment | 1951 | 3 |